PMK

Platform for web processing for pharmaceuticals, medical and diagnostics (continuous)

Description

PMK is a freely configurable production platform for web processing. Standard core processes such as sealing, cutting and punching are combined depending on the product with individually coordinated technology modules. So, based on the PMK, for example, transdermal therapeutic system (TTS/TDS) can be produced as well as Oral Dissolvable Films (ODF) or diagnostic test strips. The ability to replace individual modules makes it possible to easily retrofit the system to produce product variants.

Benefits
  • Pharmaceutical GMP design; modular setup with a choice of different stations
  • Slight and variably adjustable web tension
  • Integrated film handling, punching and sealing
  • Labeling, marking and printing, including inspection system
  • Welding and hemming processes using thermal, laser and ultrasonic technology
  • Inspection processes such as leak tightness and flow inspections, plus pressure, force, weight and torque measurements up to overall functions testing
  • PMK - cutting and spreading oral dissolvable films (ODF)

    The thin web material for ODF is cut into individual strips and spread over a pre-defined distance

  • PMK - cross-section of oral film strips (ODF)

    Longitudinal and cross-cutting of sensitive oral film strips (ODF)

  • PMK - sealing station for four-edge sealing bags

    The four-edge sealing bags for ODF are securely sealed in the PMK sealing station

  • PMK 300 – production machine for medium and large series

    The PMK 300 for medium and high speeds is suitable for processing web widths of up to 300 mm

  • PMK 150 - Flexible web processing up to a width of 150 mm

    Web material with a width of up to 150 mm can be processed on the flexible PMK 150 platform

  • PMK 300 - Modularly designed platform for manufacturing multi-layer products

    The modular design of the PMK 300 makes it possible to produce a wide range of multi-layer products such as TTS/TDS patches

  • PMK 700 - Production machines for roll material up to a width of 700 mm

    Roll material with a width of up to 700 mm can be processed on the PMK 700 platform, for example for medical products

  • PMK - Delivery of ODF on the packaging material

    Oral film strips (ODF) are accurately placed in position on the packaging material

  • PMK - Exact contour cuts

    Exact contour cuts and winding of the cutting waste

  • PMK - Quality inspection with camera systems

    Camera systems are used for quality inspection in the PMK. Among other things, they inspect position and location accuracy as well as the printing

Technical data
  • Output: (typical): 200-400 products per web and minute
  • Output: (maximum): 750 products per web and minute
  • Common design: 1-3 webs
  • A maximum of 8 webs is possible
  • Web width: 150-700mm
Final products
  • ODF – Oral Dissolvable Film
  • TDS – Matrix patch standard/ special design
  • TDS – Reservoir patch
  • TTS – Transdermal therapeutic systems
  • Diagnostic test strips and biosensors
  • Classic dressing
  • Medical products for dressing wounds
  • etc.
Periphery
  • Packaging machines

Machine features

Web handling

Perfect web handling: Technical highly sensible components regulate feeding, transport and ejection of materials within the machine. Dancers, web edge controls, and winding and rewinding devices are the basic technologies for producing items such as patches.

Punching

The punching processes in a web processing system require the highest degree of precision and quality of raw materials in order to achieve the high outputs required during continuous operation, while also guaranteed the necessary accuracy. To achieve this, we use solid punching tools and die punching, in our machines.

Sealing

Sealing is one of the central processes when connecting several product layers. We apply several technologies for this process. Depending on the material characteristics, we use such applications as platen sealing, roller sealing (hot and cold), pulse sealing, ultrasonic sealing or thermal sealing.

Camera inspection

Position and location accuracy, products in the sealing area, color deviations, damage or soiling to the detection of particles using sensor technology: Powerful camera systems are essential in quality inspection.

Applications

Navel patch heals abdominal pain

The Shanxi Yabao Pharmaceutical Group produces homeopathic patches for the Chinese market. The “gingerbread” patch is manufactured on a Packing and Four-Side Sealing Machine from Harro Höfliger.

Made in Japan – TTS/TDS products

When it comes to the production of patches for the treatment of asthma and pain Nipro Patch relies on Harro Höfliger’s many years of expertise in web converting as well as in transdermal systems.

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