Behind any multi-layered product made of web materials for transdermal therapeutic systems (TTS/TDS) and oral (ODF) or muccoadhesive buccal (MBF) film strips are complex production technologies. As the technology leader in the processing and customization of roll materials, for decades Harro Höfliger has been playing an important role in influencing technological advances in the industry. Modular machine concepts allow the flexible production and packaging of transdermal and oral products.
All processes for manufacturing these patches and film strips are designed towards high product safety and careful handling of the active ingredients. TTS/TDS such as matrix and reservoir patches as well as oral and buccal film strips are manufactured in compliance with pharmaceutical standards. They are then securely packaged in four-side sealed sachets, which are designed to be easy and intuitive for the user to open.
For production of TTS/TDS and ODF/MBF, all processes are designed towards high product safety and carefully handling raw materials. Thus, transdermal systems such as matrix and reservoir patches, iontophoresis and needle patches as well as filmstrips are produced according to GMP guidelines.
In the manufacturing of multi-layer products, what is essential is to be fully knowledgeable of the properties and behavior of the individual web materials. With our many years of experience we offer individual solutions using modular technologies, unique in their combination and based on extensive PoP.
There are various coating processes possible to precisely apply the active ingredient-containing and functional polymer matrix onto a substrate. We combine our expertise with that of our technology partners to determine the specific high-precision coating technique in order to meet the product requirements.
Precise laminating and punching is important in the manufacturing of diagnostic products made of web materials
Production and packaging of active-ingredient dissolvable film strips (ODF)
Production of iontophoresis patches comprises not only web processing and dosing, but also assembly of conductive strips
Production of transdermal patches for asthma treatment, followed by primary packaging into bags
Manufacture of topical patches and packaging in ziplock sachets.
Manufacture and packaging of oral and muccoadhesive buccal films (ODF/MBF).
Oral (ODF) and buccal (MBF) film strips offer huge potential for the pharmaceutical market. Harro Höfliger has a well-established machine program for the production and packaging of film strips.
When it comes to the production of patches for the treatment of asthma and pain Nipro Patch relies on Harro Höfliger’s many years of expertise in web converting as well as in transdermal systems.
Director Web Converting Technology
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