Microneedle systems and Microneedle Array Patches (MAP) are a promising platform for the delivery of drug substances. These systems are being intensively researched, for instance as an alternative to conventional vaccine delivery via syringes. The extremely small needles penetrate the uppermost skin layer and deliver the active substances locally or into the body via the blood-stream. In addition to drug-coated or hollow filled microneedles, which are applied using an individual device or a patch, there are also developments of needles that dissolve completely after application. They consist of the drug (API) embedded into a soluble matrix.
As a specialist for innovative process solutions and an expert in injectables and patches, Harro Höfliger actively supports the development of this future technology.
A clean, aseptic environment is essential for the manufacture, coating, drying, filling and packaging of sterile microneedle-based systems. Harro Höfliger's concepts are tailored to your specific needs and range from laminar flow systems to isolators.
Microneedle Array Patches (MAP), which contain a large number of needles with active ingredient, are applied to the skin using a plastic device. At Harro Höfliger, the often complex assembly processes of such small devices can be tested and then be reliably scaled to production format.
Our flexible processes in the manufacture of patches also allow the production, handling and processing of microneedle patches. All processes are designed for high product safety and gentle handling of the delicate needles.
Manufacturing of transdermal therapeutic systems with microneedles, which release the ingredient into the skin
Director Needle Technology
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